Literature summary for 1.1.1.267 extracted from

Kim, S.; Kuzuyama, T.; Chang, Y.; Song, K.; Kim, S.
Identification of class 2 1-deoxy-D-xylulose 5-phosphate synthase and 1-deoxy-D-xylulose 5-phosphate reductoisomerase genes from Ginkgo biloba and their transcription in embryo culture with respect to ginkgolide biosynthesis (2006), Planta Med., 72, 234-240.

Search for more literature for 1.1.1.267

Cloned(Commentary)

Cloned (Comment)	Organism
DNA and amino acid sequence determination and analysis, phylogenetic tree, functional complementation of Escherichia coli DXR-knockout mutants	Ginkgo biloba

Protein Variants

Protein Variants	Comment	Organism
additional information	rescuing of Escherichia coli enzyme-knockout mutants by the Ginkgo gene clone from embryonic roots	Ginkgo biloba

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1-deoxy-D-xylulose 5-phosphate + NADPH + H+	Ginkgo biloba	the enzyme catalyzes the second committed step in the 2C-methyl-D-erythritol 4-phosphate pathway for biosynthesis of isopentenyl diphosphate	2-C-methyl-D-erythritol 4-phosphate + NADP+	-	?

Organism

Organism	UniProt	Comment	Textmining
Ginkgo biloba	Q5J7B3	DXR-like mRNA	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
embryo	root	Ginkgo biloba	-
leaf	-	Ginkgo biloba	-
root	embryonic, higher expression level	Ginkgo biloba	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1-deoxy-D-xylulose 5-phosphate + NADPH + H+	-	Ginkgo biloba	2-C-methyl-D-erythritol 4-phosphate + NADP+	-	?
1-deoxy-D-xylulose 5-phosphate + NADPH + H+	the enzyme catalyzes the second committed step in the 2C-methyl-D-erythritol 4-phosphate pathway for biosynthesis of isopentenyl diphosphate	Ginkgo biloba	2-C-methyl-D-erythritol 4-phosphate + NADP+	-	?

Synonyms

Synonyms	Comment	Organism
1-deoxy-D-xylulose 5-phosphate reductoisomerase	-	Ginkgo biloba
DXR	-	Ginkgo biloba

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Ginkgo biloba

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Release 2023.1 (January 2023)