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Literature summary for 1.1.1.271 extracted from
- An epimerase-reductase in L-fucose synthesis (1988), J. Biol. Chem., 263, 1693-1697.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.014 | - |
GDP-4-keto-6-deoxy-D-mannose | - |
Sus scrofa |  |
| 0.023 | - |
NADH | - |
Sus scrofa | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 31500 | - |
SDS-PAGE | Sus scrofa |
| 63100 | - |
gel filtration | Sus scrofa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| homogeneity | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| thyroid gland | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.194 | - |
- |
Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GDP-4-dehydro-6-deoxy-alpha-D-mannose + NADH + H+ | - |
Sus scrofa | GDP-beta-L-fucose + NAD+ | - |
r | |
| GDP-4-keto-6-deoxy-D-mannose + NADPH | enzyme uses NADH as cofactor | Sus scrofa | GDP-6-deoxy-L-galactose + NADP+ | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | two similar subunits | Sus scrofa |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.9 | - |
- |
Sus scrofa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Sus scrofa | |
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