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Literature summary for 1.1.1.28 extracted from

  • Okano, K.; Yoshida, S.; Yamada, R.; Tanaka, T.; Ogino, C.; Fukuda, H.; Kondo, A.
    Improved production of homo-D-lactic acid via xylose fermentation by introduction of xylose assimilation genes and redirection of the phosphoketolase pathway to the pentose phosphate pathway in L-Lactate dehydrogenase gene-deficient Lactobacillus plantarum (2009), Appl. Environ. Microbiol., 75, 7858-7861.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information due to the presence of the pentose phosphate pathway, wild-type strain IO-1 produces only L-lactic acid, disruption of the phosphoketolase pathway by deletion of the phosphoketolase 1 gene xpk1 in the L-lactate dehydrogenase gene ldhL1-deficient DELTAxpk1,DELTAldhL1 NCIMB 8826 strain results in strain DELTAldhL1 NCIMB 8826, which produces optically pure D-lactic acid, introduction of the pentose phosphate pathway by introduction of the transketolase gene from Lactococcus lactis IL 1403 into this strain. Xylose fermentation by the mutant strains, overview Lactiplantibacillus plantarum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Lactiplantibacillus plantarum strain NCIMB 8826 produces optically pure D-lactic acid ?
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additional information Lactiplantibacillus plantarum NCIMB 8826 strain NCIMB 8826 produces optically pure D-lactic acid ?
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?
additional information Lactiplantibacillus plantarum NCIMB 8826 delta ldhL1 -xpk1::tkt-delta xpk strain NCIMB 8826 produces optically pure D-lactic acid ?
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?

Organism

Organism UniProt Comment Textmining
Lactiplantibacillus plantarum
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Lactiplantibacillus plantarum NCIMB 8826
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information strain NCIMB 8826 produces optically pure D-lactic acid Lactiplantibacillus plantarum ?
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?
additional information strain NCIMB 8826 produces optically pure D-lactic acid Lactiplantibacillus plantarum NCIMB 8826 ?
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?
additional information strain NCIMB 8826 produces optically pure D-lactic acid Lactiplantibacillus plantarum NCIMB 8826 delta ldhL1 -xpk1::tkt-delta xpk ?
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?

General Information

General Information Comment Organism
metabolism in the organism, xylose is converted into lactic and acetic acids by xylose isomerization by xylose isomerase to xylulose, which is phosphorylated to xylulose 5-phosphate by xylulokinase. Through the phosphoketolase pathway, xylulose 5-phosphate is finally converted to lactic acid and acetic acid in a process known as hetero-lactic acid fermentation Lactiplantibacillus plantarum