Inhibitors | Comment | Organism | Structure |
---|---|---|---|
12-oxododecanoic acid | linear competitive | Rattus norvegicus | |
S-formylglutathione | product inhibition with S-hydroxymethylglutathione | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.006 | - |
glutathione | - |
Rattus norvegicus | |
0.125 | - |
glutathione monomethyl ester | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
class II alcohol dehydrogenase | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
formaldehyde + 6-mercaptohexanoate + NAD+ | 30% of the activity with glutathione | Rattus norvegicus | S-formyl-6-mercaptohexenoate + NADH | - |
? | |
formaldehyde + 8-mercaptooctanoate + NAD+ | 35% of the activity with glutathione | Rattus norvegicus | S-formyl-8-mercaptooctanoate + NADH | - |
? | |
formaldehyde + captopril + NAD+ | 8% of the activity with glutathione | Rattus norvegicus | S-formylcaptopril + NADH | - |
? | |
formaldehyde + glutathione + NAD+ | the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione | Rattus norvegicus | S-formylglutathione + NADH + H+ | - |
r | |
formaldehyde + glutathione + NADP+ | - |
Rattus norvegicus | S-formylglutathione + NADPH + H+ | - |
r | |
formaldehyde + glutathione monomethyl ester + NAD+ | 70% of the activity with glutathione | Rattus norvegicus | S-formylglutathione monomethyl ester + NADH | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Rattus norvegicus |