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Literature summary for 1.1.1.284 extracted from

  • Lee, U.; Wie, C.; Fernandez, B.O.; Feelisch, M.; Vierling, E.
    Modulation of nitrosative stress by S-nitrosoglutathione reductase is critical for thermotolerance and plant growth in Arabidopsis (2008), Plant Cell, 20, 786-802.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.284

Protein Variants

Protein Variants Comment Organism
E283K activity compared with the wild type is 33.8% in hot5-1 plants. No significant change in GSNOR activity under heat stress conditions in the wild-type or mutant. Dark-grown seedlings of hot5-1 have a heat-stress phenotype in the dark, despite having apparently reasonable GSNOR activity at this stage Arabidopsis thaliana
G288R activity compared with the wild type is 58.8% in hot5-3 plants. No significant change in GSNOR activity under heat stress conditions in the wild-type or mutant. Dark-grown seedlings of hot5-3 have a heat-stress phenotype in the dark, despite having apparently reasonable GSNOR activity at this stage Arabidopsis thaliana
additional information thermotolerance-defective mutant hot5, which encodes GSNOR. Hot5 missense alleles cannot acclimate to heat as dark-grown seedlings but grow normally and can heat-acclimate in the light. The null alleles cannot heat-acclimate as light-grown plants and have other phenotypes, including failure to grow on nutrient plates, increased reproductive shoots, and reduced fertility. The fertility defect of hot5 is due to both reduced stamen elongation and male and female fertilization defects. The hot5 null alleles show increased nitrate and nitroso species levels, and the heat sensitivity of both missense and null alleles is associated with increased NO species. Heat sensitivity is enhanced in wild-type and mutant plants by NO donors, and the heat sensitivity of hot5 mutants can be rescued by an NO scavenger. An NO-overproducing mutant is also defective in thermotolerance Arabidopsis thaliana

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
-
 Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Arabidopsis thaliana
-
seed dried seeds Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-nitrosoglutathione + NADH + H+
-
 Arabidopsis thaliana ?
-
 ?

Synonyms

Synonyms Comment Organism
GSNOR
-
 Arabidopsis thaliana
HOT5
-
 Arabidopsis thaliana
S-nitrosoglutathione reductase
-
 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana GSNOR is not heat induced additional information

General Information

General Information Comment Organism
physiological function importance of GSNOR-regulated NO homeostasis to abiotic stress and plant development. GSNOR affects intracellular NO/nitrosation levels Arabidopsis thaliana