Literature summary for 1.1.1.30 extracted from

Tucker, G.A.; Dawson, A.P.
The kinetics of rat liver and heart mitochondria beta-hydroxybutyrate dehydrogenase (1979), Biochem. J., 179, 579-581.

Search for more literature for 1.1.1.30

Activating Compound

Activating Compound	Comment	Organism	Structure
phosphatidylcholine	-	Rattus norvegicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.014	-	NADH	liver, soluble enzyme	Rattus norvegicus
0.029	-	NADH	heart, soluble enzyme	Rattus norvegicus
0.067	-	NAD+	heart, soluble enzyme	Rattus norvegicus
0.071	-	NAD+	liver, soluble enzyme	Rattus norvegicus
0.149	-	acetoacetate	liver, soluble enzyme	Rattus norvegicus
0.312	-	acetoacetate	heart, soluble enzyme	Rattus norvegicus
0.866	-	(R)-3-hydroxybutanoate	liver, soluble enzyme	Rattus norvegicus
0.866	-	(R)-3-hydroxybutanoate	liver-soluble enzyme, at pH 8.1 and 30°C	Rattus norvegicus
1.586	-	(R)-3-hydroxybutanoate	heart, soluble enzyme	Rattus norvegicus
1.586	-	(R)-3-hydroxybutanoate	heart-soluble enzyme, at pH 8.1 and 30°C	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(R)-3-hydroxybutanoate + NAD+	Rattus norvegicus	-	acetoacetate + NADH	-	r

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
heart	-	Rattus norvegicus	-
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(R)-3-hydroxybutanoate + NAD+	-	Rattus norvegicus	acetoacetate + NADH	-	r
(R)-3-hydroxybutanoate + NAD+	-	Rattus norvegicus	acetoacetate + NADH + H+	-	r

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Rattus norvegicus

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Release 2023.1 (January 2023)