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Literature summary for 1.1.1.300 extracted from

  • Pares, X.; Farres, J.; Kedishvili, N.; Duester, G.
    Medium- and short-chain dehydrogenase/reductase gene and protein families: Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism (2008), Cell. Mol. Life Sci., 65, 3936-3949.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.300

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens RDH10 is essential for retinoic acid biosynthesis during embryogenesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cis-6-nonenal + NADPH + H+ good substrate of RDH11 and RDH12, while RHD10 has very low activity towards this substrate Homo sapiens ?
-
 ?
additional information RDH10 is essential for retinoic acid biosynthesis during embryogenesis Homo sapiens ?
-
 ?
n-nonanal + NADPH + H+ substrate of RDH11 and RDH12 Homo sapiens n-nonanol + NADP+
-
 ?
retinal + NADPH + H+
-
 Homo sapiens retinol + NADP+
-
 ?
trans-2-nonenal + NADPH + H+ good substrate of RDH11 and RDH12, while RHD10 has very low activity towards this substrate Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
NADP+-dependent all-trans-retinol dehydrogenase
-
 Homo sapiens
RDH10
-
 Homo sapiens
RDH11
-
 Homo sapiens
RDH12
-
 Homo sapiens
retinal reductase
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Mus musculus
NADP+
-
 Homo sapiens
NADP+
-
 Rattus norvegicus
NADP+ prefers NADP+ as cofactor Homo sapiens
NADPH
-
 Mus musculus
NADPH
-
 Homo sapiens
NADPH
-
 Rattus norvegicus