Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
diacetyl + NADH + H+ | Geobacillus stearothermophilus | - |
(S)-acetoin + NAD+ | - |
? | |
diacetyl + NADH + H+ | Geobacillus stearothermophilus ATCC 2027 | - |
(S)-acetoin + NAD+ | - |
? | |
additional information | Geobacillus stearothermophilus | the enzyme shows an S-enantioselectivity in the reversible reduction of acetoin so it might be responsible of the meso-butenediol formation from R-acetoin. It acts on racemic acetoin and (S)-acetoin to form (2S,3S)-butane-2,3-diol, EC 1.1.1.76, but also on the (2R,3R)-butane-2,3-diol isomer in the reverse reaction, EC 1.1.1.4 | ? | - |
? | |
additional information | Geobacillus stearothermophilus ATCC 2027 | the enzyme shows an S-enantioselectivity in the reversible reduction of acetoin so it might be responsible of the meso-butenediol formation from R-acetoin. It acts on racemic acetoin and (S)-acetoin to form (2S,3S)-butane-2,3-diol, EC 1.1.1.76, but also on the (2R,3R)-butane-2,3-diol isomer in the reverse reaction, EC 1.1.1.4 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Geobacillus stearothermophilus | - |
- |
- |
Geobacillus stearothermophilus ATCC 2027 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native enzyme by adsorption on diethylaminoethylSepharose and hydrophobic interaction chromatography | Geobacillus stearothermophilus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
diacetyl + NADH + H+ | - |
Geobacillus stearothermophilus | (S)-acetoin + NAD+ | - |
? | |
diacetyl + NADH + H+ | - |
Geobacillus stearothermophilus ATCC 2027 | (S)-acetoin + NAD+ | - |
? | |
additional information | the enzyme shows an S-enantioselectivity in the reversible reduction of acetoin so it might be responsible of the meso-butenediol formation from R-acetoin. It acts on racemic acetoin and (S)-acetoin to form (2S,3S)-butane-2,3-diol, EC 1.1.1.76, but also on the (2R,3R)-butane-2,3-diol isomer in the reverse reaction, EC 1.1.1.4 | Geobacillus stearothermophilus | ? | - |
? | |
additional information | the enzyme shows an S-enantioselectivity in the reversible reduction of acetoin so it might be responsible of the meso-butenediol formation from R-acetoin. It acts on racemic acetoin and (S)-acetoin to form (2S,3S)-butane-2,3-diol, EC 1.1.1.76, but also on the (2R,3R)-butane-2,3-diol isomer in the reverse reaction, EC 1.1.1.4 | Geobacillus stearothermophilus ATCC 2027 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BSDR | - |
Geobacillus stearothermophilus |
S-stereospecific diacetyl reductase | - |
Geobacillus stearothermophilus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
assay at | Geobacillus stearothermophilus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | dependent on | Geobacillus stearothermophilus |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the butanediol cycle, overview | Geobacillus stearothermophilus |