Literature summary for 1.1.1.339 extracted from

Nakano, Y.; Suzuki, N.; Yoshida, Y.; Nezu, T.; Yamashita, Y.; Koga, T.
Thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase synthesizing dTDP-6-deoxy-L-talose from Actinobacillus actinomycetemcomitans (2000), J. Biol. Chem., 275, 6806-6812.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Aggregatibacter actinomycetemcomitans

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
30700	-	x * 30700, SDS-PAGE	Aggregatibacter actinomycetemcomitans

Organism

Organism	UniProt	Comment	Textmining
Aggregatibacter actinomycetemcomitans	-	NCTC 9710	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
dTDP-4-dehydro-6-deoxy-beta-L-mannose + NADH + H+	-	Aggregatibacter actinomycetemcomitans	dTDP-6-deoxy-beta-L-talose + NAD+	-	?
dTDP-4-dehydro-6-deoxy-beta-L-mannose + NADH + H+	-	Aggregatibacter actinomycetemcomitans NCTC 9710	dTDP-6-deoxy-beta-L-talose + NAD+	-	?

Subunits

Subunits	Comment	Organism
?	x * 30700, SDS-PAGE	Aggregatibacter actinomycetemcomitans

Synonyms

Synonyms	Comment	Organism
dTDP-6-deoxy-L-lyxo-4-hexulose reductase	-	Aggregatibacter actinomycetemcomitans
tll	-	Aggregatibacter actinomycetemcomitans

General Information

General Information	Comment	Organism
physiological function	enzyme is part of the pathway leading to the unusual sugar, 6-deoxy-L-talose, which is a conctituent of cell wall components in some bacteria	Aggregatibacter actinomycetemcomitans

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Release 2023.1 (January 2023)