Literature summary for 1.1.1.353 extracted from

Shima, Y.; Shiina, M.; Shinozawa, T.; Ito, Y.; Nakajima, H.; Adachi, Y.; Yabe, K.
Participation in aflatoxin biosynthesis by a reductase enzyme encoded by vrdA gene outside the aflatoxin gene cluster (2009), Fungal Genet. Biol., 46, 221-231.

Search for more literature for 1.1.1.353

Cloned(Commentary)

Cloned (Comment)	Organism
-	Aspergillus parasiticus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
38566	-	x * 38566, calculated from amino acid sequence	Aspergillus parasiticus

Organism

Organism	UniProt	Comment	Textmining
Aspergillus parasiticus	B9WYE6	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
mycelium	-	Aspergillus parasiticus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1'-hydroxyversicolorone + NADPH + H+	-	Aspergillus parasiticus	versicolorone + NADP+	-	r
versiconal + NADPH + H+	-	Aspergillus parasiticus	versiconol + NADP+	-	r
versiconal hemiacetal acetate + NADPH + H+	-	Aspergillus parasiticus	versiconol acetate + NADP+	-	r

Subunits

Subunits	Comment	Organism
?	x * 38566, calculated from amino acid sequence	Aspergillus parasiticus

Synonyms

Synonyms	Comment	Organism
VHA reductase II	-	Aspergillus parasiticus
vrdA	-	Aspergillus parasiticus

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Aspergillus parasiticus

General Information

General Information	Comment	Organism
metabolism	the vrdA is not an aflatoxin biosynthesis gene, although it actually participates in aflatoxin biosynthesis in cells because of its group substrate specificity to intermediates in aflatoxin biosynthesis	Aspergillus parasiticus

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Release 2023.1 (January 2023)