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Literature summary for 1.1.1.41 extracted from

  • Ramachandran, N.; Colman, R.F.
    Evidence for the presence of two nonidentical subunits in NAD-dependent isocitrate dehydrogenase of pig heart (1978), Proc. Natl. Acad. Sci. USA, 75, 252-255.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
39000
-
alphabeta, 1 * 39000 + 1 * 41000, SDS-PAGE Sus scrofa
41000
-
alphabeta, 1 * 39000 + 1 * 41000, SDS-PAGE Sus scrofa
300000 340000 gel filtration Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isocitrate + NAD+ Sus scrofa
-
2-oxoglutarate + CO2 + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
Sus scrofa

Purification (Commentary)

Purification (Comment) Organism
-
Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
27 31
-
Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isocitrate + NAD+
-
Sus scrofa 2-oxoglutarate + CO2 + NADH + H+
-
?

Subunits

Subunits Comment Organism
dimer alphabeta, 1 * 39000 + 1 * 41000, SDS-PAGE Sus scrofa

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Sus scrofa