Literature summary for 1.1.1.49 extracted from

Merritt, J.; Butz, J.A.; Ogunnaike, B.A.; Edwards, J.S.
Parallel analysis of mutant human glucose 6-phosphate dehydrogenase in yeast using PCR colonies (2005), Biotechnol. Bioeng., 92, 519-531.

Search for more literature for 1.1.1.49

Cloned(Commentary)

Cloned (Comment)	Organism
study of functional complementation of the yeast deletion mutant strain zwf1 by human wild-type and mutant enzymes, construction of a human enzyme mutant library containing all possible single nucleotide missense mutations in the eight-residue glucose 6-phosphate binding peptide of the enzyme	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	study of functional complementation of the yeast deletion mutant strain zwf1 by human wild-type and mutant enzymes, construction of a human enzyme mutant library containing all possible single nucleotide missense mutations in the eight-residue glucose 6-phosphate binding peptide of the enzyme, all mutations of residues Asp200, His201, Lys205 lead to inactive enzymes, some mutations of residues Ile199, Leu203, Arg198, Tyr202, Gly204 result in active, some in inactive enzymes, overview	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
G6PD	-	Homo sapiens
glucose 6-phosphate dehydrogenase	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)