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Literature summary for 1.1.1.51 extracted from

  • Higo, S.; Hojo, Y.; Ishii, H.; Kominami, T.; Nakajima, K.; Poirier, D.; Kimoto, T.; Kawato, S.
    Comparison of sex-steroid synthesis between neonatal and adult rat hippocampus (2009), Biochem. Biophys. Res. Commun., 385, 62-66.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus the relative expression level of 17beta- or 3beta-hydroxysteroid dehydrogenase is approximately 1.3-1.5fold higher at the neonatal than at the adult stage Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
androstenediol + NAD(P)H + H+ reaction catalysed by 3beta-HSD (type 1) Rattus norvegicus testosterone + NAD(P)+
-
?
androstenedione + NAD(P)H + H+ reaction catalysed by 17beta-HSD (type 1 and 3) Rattus norvegicus testosterone + NAD(P)+
-
?
dehydroepiandrosterone + NAD(P)H + H+ reaction catalysed by 17beta-HSD (type 1 and 3) Rattus norvegicus androstenediol + NAD(P)+
-
?
estrone + NAD(P)H + H+ reaction catalysed by 17beta-HSD (type 1 and 3) Rattus norvegicus estradiol + NAD(P)+
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?

Synonyms

Synonyms Comment Organism
17beta-HSD (type 1)
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Rattus norvegicus
17beta-HSD (type 3)
-
Rattus norvegicus
17beta-hydroxysteroid dehydrogenase
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Rattus norvegicus
3beta-HSD (type 1)
-
Rattus norvegicus
3beta-hydroxysteroid dehydrogenase
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Rattus norvegicus