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Literature summary for 1.1.1.58 extracted from

  • Huisjes, E.H.; Luttik, M.A.; Almering, M.J.; Bisschops, M.M.; Dang, D.H.; Kleerebezem, M.; Siezen, R.; van Maris, A.J.; Pronk, J.T.
    Toward pectin fermentation by Saccharomyces cerevisiae: expression of the first two steps of a bacterial pathway for D-galacturonate metabolism (2012), J. Biotechnol., 162, 303-310.
    View publication on PubMed

Application

Application Comment Organism
synthesis expression of Lactococcus lactis uxaB and uxaC genes encoding D-tagaturonate reductase and D-galacturonate isomerase, in Saccharomyces cerevisiae to investigate in vivo activity of the first steps of the D-galacturonate pathway. Although D-tagaturonate reductase could, in principle, provide an alternative means for re-oxidizing cytosolic NADH, addition of D-galacturonate does not restore anaerobic growth, possibly due to absence of a functional D-altronate exporter in Saccharomyces cerevisiae Lactococcus lactis

Cloned(Commentary)

Cloned (Comment) Organism
expression in Saccharomyces cerevisiae Lactococcus lactis

Protein Variants

Protein Variants Comment Organism
additional information expression of Lactococcus lactis uxaB and uxaC genes encoding D-tagaturonate reductase and D-galacturonate isomerase, in Saccharomyces cerevisiae to investigate in vivo activity of the first steps of the D-galacturonate pathway. Although D-tagaturonate reductase could, in principle, provide an alternative means for re-oxidizing cytosolic NADH, addition of D-galacturonate does not restore anaerobic growth, possibly due to absence of a functional D-altronate exporter in Saccharomyces cerevisiae Lactococcus lactis

Organism

Organism UniProt Comment Textmining
Lactococcus lactis A9QSF6
-
-
Lactococcus lactis KF147 A9QSF6
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-

Synonyms

Synonyms Comment Organism
uxaB
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Lactococcus lactis