Literature summary for 1.1.1.6 extracted from

Liu, L.; Zhuge, X.; Shin, H.D.; Chen, R.R.; Li, J.; Du, G.; Chen, J.
Improved production of propionic acid in Propionibacterium jensenii via combinational overexpression of glycerol dehydrogenase and malate dehydrogenase from Klebsiella pneumoniae (2015), Appl. Environ. Microbiol., 81, 2256-2264.

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Cloned(Commentary)

Cloned (Comment)	Organism
recombinant co-overexpression of enzymes glycerol dehydrogenase, malate dehydrogenase, and fumarate hydratase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 12657 in Propionibacterium jensenii leads to increased increased propionic acid production, quantittive reverse transcription PCR expression analysis	Klebsiella pneumoniae subsp. pneumoniae

Protein Variants

Protein Variants	Comment	Organism
additional information	recombinant co-overexpression of enzymes glycerol dehydrogenase, malate dehydrogenase, and fumarate hydratase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 12657 in Propionibacterium jensenii leads to increased increased propionic acid production. The transcription levels of the corresponding enzymes in the engineered strains are 2.85 to 8.07fold higher than those in the wild type. The coexpression of GDH and MDH increases the propionic acid titer from 26.95 g/liter in wild-type to 39.43 g/liter in the engineered strains. Fed-batch culture kinetics of propionic acid production from glycerol, overview	Klebsiella pneumoniae subsp. pneumoniae

Organism

Organism	UniProt	Comment	Textmining
Klebsiella pneumoniae subsp. pneumoniae	-	-	-
Klebsiella pneumoniae subsp. pneumoniae ATCC 12657	-	-	-

Synonyms

Synonyms	Comment	Organism
GDH	-	Klebsiella pneumoniae subsp. pneumoniae

General Information

General Information	Comment	Organism
metabolism	glycerol is one of the key metabolites for propionic acid synthesis in Propionibacterium jensenii. It is a precursor for metabolic pathways for propionic acid, lactic acid, and acetic acid biosynthesis in Propionibacterium	Klebsiella pneumoniae subsp. pneumoniae

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Release 2023.1 (January 2023)