Literature summary for 1.1.1.8 extracted from

Kota, V.; Rai, P.; Weitzel, J.M.; Middendorff, R.; Bhande, S.S.; Shivaji, S.
Role of glycerol-3-phosphate dehydrogenase 2 in mouse sperm capacitation (2010), Mol. Reprod. Dev., 77, 773-783.

Search for more literature for 1.1.1.8

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
sperm	in the absence of Gpd2, hyperactivation and acrosome reaction are significantly altered, and a few changes in protein tyrosine phosphorylation are also observed during capacitation. GPD2 activity is required for generation of reactive oxygen species in mouse spermatozoa during capacitation, failing which, capacitation is impaired	Mus musculus	-

General Information

General Information	Comment	Organism
physiological function	in spermatozoa from homozygous Gpd2 deletion mice, in the absence of Gpd2, hyperactivation and acrosome reaction are significantly altered, and a few changes in protein tyrosine phosphorylation are also observed during capacitation. GPD2 activity is required for generation of reactive oxygen species in mouse spermatozoa during capacitation, failing which, capacitation is impaired	Mus musculus

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Release 2023.1 (January 2023)