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Literature summary for 1.1.1.9 extracted from

  • Gurpilhares, D.B.; Hasmann, F.A.; Pessoa, A.; Roberto, I.C.
    The behavior of key enzymes of xylose metabolism on the xylitol production by Candida guilliermondii grown in hemicellulosic hydrolysate (2009), J. Ind. Microbiol. Biotechnol., 36, 87-93.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
xylitol + NAD+ Meyerozyma guilliermondii a xylose reductase, using either NADH or NADPH, reduces D-xylose to xylitol, subsequently xylitol is oxidized to D-xylulose by the NAD+-linked xylitol dehydrogenase D-xylulose + NADH + H+
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?

Organism

Organism UniProt Comment Textmining
Meyerozyma guilliermondii
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FTI 20037, ATCC 201935
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Source Tissue

Source Tissue Comment Organism Textmining
additional information the organism grows on rice straw hemicellulosic hydrolysate, as the only source of nutrient, optimization of culture conditions for production of xylitol from D-xylose, xylitol dehydrogenase remains constant, whereas the level of xylose reductase decreases when the initial xylose concentration is increased from 30 to 70 g/l, development of enzyme activities, overview Meyerozyma guilliermondii
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
xylitol + NAD+
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Meyerozyma guilliermondii D-xylulose + NADH + H+
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?
xylitol + NAD+ a xylose reductase, using either NADH or NADPH, reduces D-xylose to xylitol, subsequently xylitol is oxidized to D-xylulose by the NAD+-linked xylitol dehydrogenase Meyerozyma guilliermondii D-xylulose + NADH + H+
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?

Synonyms

Synonyms Comment Organism
xylitol dehydrogenase
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Meyerozyma guilliermondii

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
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assay at Meyerozyma guilliermondii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.2
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assay at Meyerozyma guilliermondii

Cofactor

Cofactor Comment Organism Structure
NAD+
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Meyerozyma guilliermondii

General Information

General Information Comment Organism
metabolism key enzymes for xylitol production in yeasts are xylose reductase and xylitol dehydrogenase, overview Meyerozyma guilliermondii