Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-phospho-D-glycerate + NAD+ | Mus musculus | - |
3-phosphonooxypyruvate + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | - |
Mus musculus | - |
neuron | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-phospho-D-glycerate + NAD+ | - |
Mus musculus | 3-phosphonooxypyruvate + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3-phosphoglycerate dehydrogenase | - |
Mus musculus |
Phgdh | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme-depleted astrocytes accumulate 20fold less L-serine compared with controls | Mus musculus |
metabolism | the enzyme catalyzes the first committed step of L-serine biosynthesis | Mus musculus |