Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisol + NAD+ | Homo sapiens | isozyme 11beta-HSD2 catalyzes the oxidative reaction with cofactor NAD+ | cortisone + NADH | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
seven different women with ovarian cancer of different types, overview | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
ovarian cancer cell | expression and activity of isozyme 11beta-HSD2 in probes of seven different women with ovarian cancer of different types, overview | Homo sapiens | - |
ovary | surface epithelium | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
determination of activity of isozyme 11beta-HSD2 in ovarian cancer, overview | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisol + NAD+ | isozyme 11beta-HSD2 catalyzes the oxidative reaction with cofactor NAD+ | Homo sapiens | cortisone + NADH | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
11beta-HSD2 | - |
Homo sapiens |
type 2 11beta-hydroxysteroid dehydrogenase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |