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Literature summary for 1.1.3.23 extracted from

  • Gomez-Moreno, C.; Edmondson, D.E.
    Evidence for an aldehyde intermediate in the catalytic mechanism of thiamine oxidase (1985), Arch. Biochem. Biophys., 239, 46-52.
    View publication on PubMed
Search for more literature for 1.1.3.23

Inhibitors

Inhibitors Comment Organism Structure
pyrithiamine
-
 unidentified soil bacterium

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
thiamine + O2 unidentified soil bacterium
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
unidentified soil bacterium
-
 ATCC 25589
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
oxythiamine + O2
-
 unidentified soil bacterium ? + H2O2
-
 ?
pyrithiamine + O2
-
 unidentified soil bacterium ? + H2O2
-
 ?
thiamine + O2 reaction via an aldehyde intermediate which is not released unidentified soil bacterium thiamine acetate + H2O2
-
 ir
thiamine + O2
-
 unidentified soil bacterium ?
-
 ?
thiamine acetic acid + H2O2
-
 unidentified soil bacterium thiamine + O2 + H2O
-
 r

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
5
-
 H2O2 release of H+ unidentified soil bacterium

Cofactor

Cofactor Comment Organism Structure
FAD 8-alpha-N(1)-histidyl-FAD unidentified soil bacterium
FAD 1 mol/mol enzyme unidentified soil bacterium