KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0037 | - |
4-Propylphenol | - |
Penicillium simplicissimum | |
0.009 | - |
4-Ethylphenol | - |
Penicillium simplicissimum | |
0.031 | - |
4-Methylphenol | - |
Penicillium simplicissimum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Penicillium simplicissimum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-ethylphenol + O2 | transient intermediate: p-quinone methide of the aromatic substrate in complex with reduced enzyme. Ordered sequential binding mechanism in which the rate of flavin reduction determines the turnover rate while the reduced enzyme-p-quinone methide binary complex rapidly reacts with dioxygen | Penicillium simplicissimum | 1-(4'-hydroxyphenyl)ethanol + 4-vinylphenol + 4-hydroxyacetophenone | - |
? | |
4-Methylphenol + O2 | transient intermediate: p-quinone methide of the aromatic substrate in complex with reduced enzyme. Ordered sequential binding mechanism in which the rate of flavin reduction determines the turnover rate while the reduced enzyme-p-quinone methide binary complex rapidly reacts with dioxygen | Penicillium simplicissimum | ? | - |
? | |
4-Propylphenol + O2 | - |
Penicillium simplicissimum | 1-(4'-Hydroxyphenyl)propanol + 4-propenylphenol + 1-(4'-hydroxyphenyl)propanone | - |
? | |
propylphenol + O2 | - |
Penicillium simplicissimum | ? | - |
r |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
4-Methylphenol | - |
Penicillium simplicissimum | |
2.5 | - |
4-Ethylphenol | - |
Penicillium simplicissimum | |
4.2 | - |
4-n-Propylphenol | - |
Penicillium simplicissimum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
flavin | a covalent 5-(4'-hydroxybenzyl)-FAD adduct is formed during reaction with 4-methylphenol | Penicillium simplicissimum |