Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | soluble enzyme sGDH | Acinetobacter calcoaceticus | 5737 | - |
membrane | bound, enzyme mGDH | Escherichia coli | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | required, interacts with PQQ cofactor | Escherichia coli | |
Ca2+ | required, interacts with PQQ cofactor | Acinetobacter calcoaceticus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose + ? | Acinetobacter calcoaceticus | physiological electron acceptor in not known | D-glucono-1,5-lactone + ? | - |
? | |
D-glucose + ubiquinone | Escherichia coli | a pivotal PQQ-containing quinoprotein coupled to the respiratory chain in the periplasmic oxidation of alcohols and sugars | D-glucono-1,5-lactone + ubiquinol | - |
? | |
additional information | Escherichia coli | evolutionary analysis of PQQ-containing proteins, overview | ? | - |
? | |
additional information | Acinetobacter calcoaceticus | evolutionary analysis of PQQ-containing proteins, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acinetobacter calcoaceticus | P13650 | - |
- |
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol | active site structure | Acinetobacter calcoaceticus | |
D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol | active site structure, putative catalytic mechanism and cycle involving Asp466 and Lys493 | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose + ? | physiological electron acceptor in not known | Acinetobacter calcoaceticus | D-glucono-1,5-lactone + ? | - |
? | |
D-glucose + ubiquinone | - |
Acinetobacter calcoaceticus | D-glucono-1,5-lactone + ubiquinol | - |
? | |
D-glucose + ubiquinone | a pivotal PQQ-containing quinoprotein coupled to the respiratory chain in the periplasmic oxidation of alcohols and sugars | Escherichia coli | D-glucono-1,5-lactone + ubiquinol | - |
? | |
D-glucose + ubiquinone | with ubiquinone-8 as minor compound, PQQ acts in electron transfer between enzyme and ubiquinone | Escherichia coli | D-glucono-1,5-lactone + ubiquinol | - |
? | |
additional information | evolutionary analysis of PQQ-containing proteins, overview | Escherichia coli | ? | - |
? | |
additional information | evolutionary analysis of PQQ-containing proteins, overview | Acinetobacter calcoaceticus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | (alpha)2, functional subunit composition, domain and overall structure analysis | Acinetobacter calcoaceticus |
monomer | functional subunit composition, domain and overall structure analysis | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
glucose dehydrogenase | - |
Escherichia coli |
glucose dehydrogenase | - |
Acinetobacter calcoaceticus |
mGDH | - |
Escherichia coli |
sGDH | - |
Acinetobacter calcoaceticus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyrroloquinoline quinone | i.e. PQQ, dependent on | Acinetobacter calcoaceticus | |
pyrroloquinoline quinone | i.e. PQQ, dependent on exogenous PQQ, since Escherichia coli does not synthesize PQQ itself | Escherichia coli |