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Literature summary for 1.1.5.4 extracted from

  • Kather, B.; Stingl, K.; van der Rest, M.E.; Altendorf, K.; Molenaar, D.
    Another unusual type of citric acid cycle enzyme in Helicobacter pylori: the malate:quinone oxidoreductase (2000), J. Bacteriol., 182, 3204-3209.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.5.4

Cloned(Commentary)

Cloned (Comment) Organism
expression of the HP0086 sequence from a plasmid induces high MQO activity in mqo deletion mutants of Escherichia coli or Corynebacterium glutamicum Helicobacter pylori

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Helicobacter pylori 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Helicobacter pylori the enzyme is part of both the electron transfer chain and the citric acid cycle ?
-
 ?

Organism

Organism UniProt Comment Textmining
Helicobacter pylori O24913
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + oxidized 2,6-dichlorophenol indophenol the route of electrons in this assay is unclear, but it probably leads from the enzyme either directly or via quinones to 2,6-dichlorophenol indophenol. The malate-dependent 2,6-dichlorophenol indophenol reduction rate catalyzed by Helicobacter pylori membranes could be stimulated by 30 to 50% by the addition of 60 mM ubiquinone-1. This suggests that quinones play, at least in part, an intermediary role in the reduction of the dye Helicobacter pylori oxaloacetate + reduced 2,6-dichlorophenol indophenol
-
 ?
additional information the enzyme is part of both the electron transfer chain and the citric acid cycle Helicobacter pylori ?
-
 ?

Synonyms

Synonyms Comment Organism
malate:quinone oxidoreductase
-
 Helicobacter pylori

Cofactor

Cofactor Comment Organism Structure
ubiquinone-1 the route of electrons in this assay is unclear, but it probably leads from the enzyme either directly or via quinones to 2,6-dichlorophenol indophenol. The malate-dependent 2,6-dichlorophenol indophenol reduction rate catalyzed by Helicobacter pylori membranes could be stimulated by 30 to 50% by the addition of 60 mM ubiquinone-1. This suggests that quinones play, at least in part, an intermediary role in the reduction of the dye Helicobacter pylori