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Literature summary for 1.10.3.1 extracted from
- Catecholase activity associated with copper-S100B (2003), Biochemistry, 42, 4392-4397.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0000194 | - |
L-noradrenaline | pH 7.2, 20°C | Bos taurus |  |
| 0.0000239 | - |
L-adrenaline | pH 7.2, 20°C | Bos taurus | |
| 0.000219 | - |
D-Dopa | pH 7.2, 20°C | Bos taurus | |
| 0.000223 | - |
L-Dopa | pH 7.2, 20°C | Bos taurus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| copper | the copper centers in the protein are directly involved in the catechol oxidation | Bos taurus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Bos taurus | extremely low levels of activity suggest that this protein likely plays no direct metabolic role in the biodegradation of catecholamines | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-dopa + 1/2 O2 | - |
Bos taurus | D-dopaquinone + H2O | - |
? | |
| L-adrenaline + O2 | - |
Bos taurus | ? | - |
? | |
| L-dopa + 1/2 O2 | - |
Bos taurus | L-dopaquinone + H2O | - |
? | |
| L-noradrenaline + O2 | - |
Bos taurus | ? | - |
? | |
| additional information | extremely low levels of activity suggest that this protein likely plays no direct metabolic role in the biodegradation of catecholamines | Bos taurus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| copper-S100B | - |
Bos taurus |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0000000912 | - |
L-noradrenaline | pH 7.2, 20°C | Bos taurus | |
| 0.00000148 | - |
L-adrenaline | pH 7.2, 20°C | Bos taurus | |
| 0.000338 | - |
D-Dopa | pH 7.2, 20°C | Bos taurus | |
| 0.000459 | - |
L-Dopa | pH 7.2, 20°C | Bos taurus | |
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Release 2023.1 (January 2023)
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