Literature summary for 1.10.3.11 extracted from

Williams, B.A.; Elliot, C.; Burri, L.; Kido, Y.; Kita, K.; Moore, A.L.; Keeling, P.J.
A broad distribution of the alternative oxidase in microsporidian parasites (2010), PLoS Pathog., 6, e1000761.

Search for more literature for 1.10.3.11

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli strain C41 membranes and in Saccharomyces cerevisiae	Antonospora locustae
expressed in Escherichia coli strain C41 membranes and in Saccharomyces cerevisiae	Trachipleistophora hominis

Inhibitors

Inhibitors	Comment	Organism	Structure
ascofuranone	almost complete inhibition at 10 nM	Antonospora locustae
ascofuranone	almost complete inhibition at 10 nM	Trachipleistophora hominis
additional information	the enzyme is cyanide- and antimycin-resistant	Antonospora locustae
additional information	the enzyme is cyanide- and antimycin-resistant	Trachipleistophora hominis

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Antonospora locustae	5739	-
mitochondrion	-	Trachipleistophora hominis	5739	-

Organism

Organism	UniProt	Comment	Textmining
Antonospora locustae	-	-	-
Trachipleistophora hominis	-	-	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.1	-	recombinant enzyme, in the presence of 10 nM ascofuranone, at 25°C, in 50 mM Tris-HCl (pH 7.4)	Trachipleistophora hominis
0.2	-	recombinant enzyme, in the presence of 10 nM ascofuranone, at 25°C, in 50 mM Tris-HCl (pH 7.4)	Antonospora locustae
1.6	-	recombinant enzyme, at 25°C, in 50 mM Tris-HCl (pH 7.4)	Trachipleistophora hominis
2.2	-	recombinant enzyme, at 25°C, in 50 mM Tris-HCl (pH 7.4)	Antonospora locustae

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ubiquinol-1 + O2	-	Antonospora locustae	ubiquinone-1 + H2O	-	?
ubiquinol-1 + O2	-	Trachipleistophora hominis	ubiquinone-1 + H2O	-	?

Synonyms

Synonyms	Comment	Organism
alternative oxidase	-	Antonospora locustae
alternative oxidase	-	Trachipleistophora hominis
AOX	-	Antonospora locustae
AOX	-	Trachipleistophora hominis

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Release 2023.1 (January 2023)