Literature summary for 1.10.3.5 extracted from

Parli, C.J.; Krieter, P.; Schmidt, B.
Metabolism of 6-chlorotryptophan to 4-chloro-3-hydroxyanthranilic acid: a potent inhibitor of 3-hydroxyanthranilic acid oxidase (1980), Arch. Biochem. Biophys., 203, 161-166.

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Inhibitors

Inhibitors	Comment	Organism	Structure
4-Chloro-3-hydroxyanthranilate	irreversible inhibition	Cavia porcellus
4-Chloro-3-hydroxyanthranilate	irreversible inhibition	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Cavia porcellus	-	guinea pig	-
Rattus norvegicus	-	Wistar	-
Rattus norvegicus Wistar	-	Wistar	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
kidney	-	Cavia porcellus	-
kidney	-	Rattus norvegicus	-
liver	-	Cavia porcellus	-
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2 3-hydroxyanthranilic acid + 2 O2	-	Cavia porcellus	2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2	-	?
2 3-hydroxyanthranilic acid + 2 O2	-	Rattus norvegicus	2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2	-	?
2 3-hydroxyanthranilic acid + 2 O2	-	Rattus norvegicus Wistar	2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2	-	?
3-hydroxy-L-kynurenine + O2	-	Rattus norvegicus	(2S)-2-amino-4-(6-imino-5-oxocyclohexa-1,3-dien-1yl)-4-oxo-butanoic acid + H2O2	-	?
3-hydroxy-L-kynurenine + O2	-	Rattus norvegicus Wistar	(2S)-2-amino-4-(6-imino-5-oxocyclohexa-1,3-dien-1yl)-4-oxo-butanoic acid + H2O2	-	?

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Release 2023.1 (January 2023)