Application | Comment | Organism |
---|---|---|
additional information | an assay for sperm PHGPx activity emerges as a unique tool to evaluate semen quality for sire selection | Bos taurus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
selenium | - |
Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + a lipid hydroperoxide | Bos taurus | - |
glutathione disulfide + lipid + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
bull, three Italian beef breeds, Chianina, Marchigiana, Romagnola | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
spermatozoon | - |
Bos taurus | - |
testis | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.04 | - |
low-PHGPx group | Bos taurus |
0.0539 | - |
low-PHGPx, Chianina | Bos taurus |
0.056 | - |
low-PHGPx, Marchigiana | Bos taurus |
0.0746 | - |
low-PHGPx, Romagnola | Bos taurus |
0.13 | - |
high-PHGPx group | Bos taurus |
0.2242 | - |
high-PHGPx, Chianina | Bos taurus |
0.2447 | - |
high-PHGPx, Romagnola | Bos taurus |
0.2453 | - |
high-PHGPx, Marchigiana | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + a lipid hydroperoxide | - |
Bos taurus | glutathione disulfide + lipid + H2O | - |
? | |
glutathione + phosphatidylcholine hydroperoxide | activity assay | Bos taurus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GPx4 | - |
Bos taurus |
PHGPX | - |
Bos taurus |
phospholipid hydroperoxide glutathione peroxidase | - |
Bos taurus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
23 | - |
activity assay at room temperature | Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
activity assay | Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
glutathione | - |
Bos taurus |
Organism | Comment | Expression |
---|---|---|
Bos taurus | PHGPx expression is up-regulated in spermatozoa by unknown mechanisms | up |