Literature summary for 1.11.1.21 extracted from

Carpena, X.; Loprasert, S.; Mongkolsuk, S.; Switala, J.; Loewen, P.C.; Fita, I.
Catalase-peroxidase KatG of Burkholderia pseudomallei at 1.7A resolution (2003), J. Mol. Biol., 327, 475-489.

Search for more literature for 1.11.1.21

Application

Application	Comment	Organism
medicine	the enzyme responsible for the activation of isoniazid as an antibiotic	Burkholderia pseudomallei

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli strain UM262	Burkholderia pseudomallei

Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging drop vapor diffusion method, using 16-20% (w/v) PEG 4K, 20% (v/v) 2-methyl-2,4-pentanediol and 0.1 M sodium citrate pH 5.6, at 20°C	Burkholderia pseudomallei

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Na+	the enzyme possesses one Na+ per subunit	Burkholderia pseudomallei

Organism

Organism	UniProt	Comment	Textmining
Burkholderia pseudomallei	Q939D2	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Burkholderia pseudomallei

Subunits

Subunits	Comment	Organism
homodimer	x-ray crystallography	Burkholderia pseudomallei

Synonyms

Synonyms	Comment	Organism
KatG	-	Burkholderia pseudomallei

Cofactor

Cofactor	Comment	Organism	Structure
heme	-	Burkholderia pseudomallei

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)