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Literature summary for 1.11.1.5 extracted from

  • Giles, S.S.; Perfect, J.R.; Cox, G.M.
    Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans (2005), Fungal Genet. Biol., 42, 20-29.
    View publication on PubMed
Search for more literature for 1.11.1.5

Protein Variants

Protein Variants Comment Organism
additional information disruption and deletion mutants show intracellular growth defects in macrophage like cells in vitro. The enzyme provides protection against oxidative stress within macrophages in vitro Cryptococcus neoformans

Inhibitors

Inhibitors Comment Organism Structure
H2O2 at a concentration of 8% and 16% can inhibit the growth of wild-type strain H99 Cryptococcus neoformans

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Cryptococcus neoformans 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ferrocytochrome c + H2O2 Cryptococcus neoformans
-
 ferricytochrome c + H2O
-
 ?
ferrocytochrome c + H2O2 Cryptococcus neoformans H99
-
 ferricytochrome c + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Cryptococcus neoformans Q6URB0
-
-
Cryptococcus neoformans H99 Q6URB0
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ferrocytochrome c + H2O2
-
 Cryptococcus neoformans ferricytochrome c + H2O
-
 ?
ferrocytochrome c + H2O2 antioxidant defense Cryptococcus neoformans ferricytochrome c + H2O
-
 ?
ferrocytochrome c + H2O2
-
 Cryptococcus neoformans H99 ferricytochrome c + H2O
-
 ?
ferrocytochrome c + H2O2 antioxidant defense Cryptococcus neoformans H99 ferricytochrome c + H2O
-
 ?