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Literature summary for 1.11.1.5 extracted from

  • Dicarlo, C.M.; Vitello, L.B.; Erman, J.E.
    Effect of active site and surface mutations on the reduction potential of yeast cytochrome c peroxidase and spectroscopic properties of the oxidized and reduced enzyme (2007), J. Inorg. Biochem., 101, 603-613.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
A193F surface mutant, shift in reduction potential to -170 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
D146N surface mutant, shift in reduction potential to -173 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
D146N/D148N surface mutant, shift in reduction potential to -173 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
D235A proximal pocket mutant, shift in reduction potential to -78 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
D235E proximal pocket mutant, shift in reduction potential to -113 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
D235N proximal pocket mutant, shift in reduction potential to -79 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
D34N surface mutant, shift in reduction potential to -175 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
E290N surface mutant, shift in reduction potential to -177 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
E291Q surface mutant, shift in reduction potential to -162 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
E32Q surface mutant, shift in reduction potential to -168 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
H52D distal pocket mutant, shift in reduction potential to -221 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
H52E distal pocket mutant, reduction potential -183 mV, comparable to wild-type Saccharomyces cerevisiae
H52K distal pocket mutant, shift in reduction potential to -157 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
H52L distal pocket mutant, shift in reduction potential to -170 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
H52L/W191F proximal pocket mutant, shift in reduction potential to -151 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
H52N | distal pocket mutant, shift in reduction potential to -259 mV, most negative reduction potential of all mutants analyzed. Analysis of spectroscopic properties Saccharomyces cerevisiae
H52Q distal pocket mutant, shift in reduction potential to -224 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
R48A/W51A/H52A distal pocket mutant, shift in reduction potential to -163 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
R48E distal pocket mutant, shift in reduction potential to -179 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
R48K distal pocket mutant, reduction potential -186 mV, comparable to wild-type. Analysis of spectroscopic properties Saccharomyces cerevisiae
R48L distal pocket mutant, shift in reduction potential to -164 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
R48L/W51L/H52L distal pocket mutant, shift in reduction potential to -146 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
R48V/W51V/H52V distal pocket mutant, shift in reduction potential to -150 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
W191F proximal pocket mutant, shift in reduction potential to -202 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
W51H distal pocket mutant, shift in reduction potential to -200 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae
W51H/H52L distal pocket mutant, shift in reduction potential to -162 mV. Analysis of spectroscopic properties Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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