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Literature summary for 1.11.2.2 extracted from

  • Rosen, H.; Crowley, J.R.; Heinecke, J.W.
    Human neutrophils use the myeloperoxidase-hydrogen peroxide-chloride system to chlorinate but not nitrate bacterial proteins during phagocytosis (2002), J. Biol. Chem., 277, 30463-30468.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
phagolysosome
-
Homo sapiens 32010
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neutrophil
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Cl- + H2O2 + H+
-
Homo sapiens HClO + H2O
-
?

Synonyms

Synonyms Comment Organism
MPO
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
heme
-
Homo sapiens

General Information

General Information Comment Organism
physiological function human neutrophils use the myeloperoxidase-hydrogen peroxide-chloride system to chlorinate but not nitrate Escherichia coli proteins during phagocytosis Homo sapiens