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Literature summary for 1.12.99.6 extracted from

  • Shaw, A.J.; Hogsett, D.A.; Lynd, L.R.
    Identification of the [FeFe]-hydrogenase responsible for hydrogen generation in Thermoanaerobacterium saccharolyticum and demonstration of increased ethanol yield via hydrogenase knockout (2009), J. Bacteriol., 191, 6457-6464.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information deletion of the hfs gene results in a loss of detectable methyl viologen-linked hydrogenase activity. Strains with a deletion of the hfs genes exhibit a 95% reduction in hydrogen and acetic acid production. DELTAhfs strain produces primarily lactic acid in place of acetic acid, resulting in an ethanol yield relatively the same as the wild-type strain yield. A strain with hfs and ldh deletions exhibit an increased ethanol yield from consumed carbohydrates Thermoanaerobacterium saccharolyticum

Organism

Organism UniProt Comment Textmining
Thermoanaerobacterium saccharolyticum
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.92
-
methyl viologen reduction by H2 Thermoanaerobacterium saccharolyticum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
H2 + oxidized methyl viologen
-
Thermoanaerobacterium saccharolyticum H+ + reduced methyl viologen
-
?

Synonyms

Synonyms Comment Organism
Hfs
-
Thermoanaerobacterium saccharolyticum
hydrogenase-Fe-S
-
Thermoanaerobacterium saccharolyticum
[FeFe]-hydrogenase
-
Thermoanaerobacterium saccharolyticum