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Literature summary for 1.13.11.1 extracted from

  • Suzuki, K.; Ichimura, A.; Ogawa, N.; Hasebe, A.; Miyashita, K.
    Differential expression of two catechol 1,2-dioxygenases in Burkholderia sp. strain TH2 (2002), J. Bacteriol., 184, 5714-5722.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.13.11.1

Cloned(Commentary)

Cloned (Comment) Organism
cat1 and cat2, expression in Escherichia coli Burkholderia sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
catechol + O2 Burkholderia sp. both catechol dioxygenases, CatA1 and CatA2 are produced in benzoate-grown cells, CatA1 is undetectable when strain TH2 is grown on 2-chlorobenzoate or cis,cis-muconate. Production of CatA1 during growth on 2-chlorobenzoate or cis,cis-muconate is observed when cat2 genes are disrupted. The inducer of Cat1 is benzoate. cis,cis-Muconate or its metabolite acts as an inducer for CatA2. Genes are not indispensable for growth of strain TH2 on 2-chlorobenzoate, they are advantageous cis,cis-muconate
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 ?
catechol + O2 Burkholderia sp. TH2 both catechol dioxygenases, CatA1 and CatA2 are produced in benzoate-grown cells, CatA1 is undetectable when strain TH2 is grown on 2-chlorobenzoate or cis,cis-muconate. Production of CatA1 during growth on 2-chlorobenzoate or cis,cis-muconate is observed when cat2 genes are disrupted. The inducer of Cat1 is benzoate. cis,cis-Muconate or its metabolite acts as an inducer for CatA2. Genes are not indispensable for growth of strain TH2 on 2-chlorobenzoate, they are advantageous cis,cis-muconate
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 ?

Organism

Organism UniProt Comment Textmining
Burkholderia sp. Q8GAY6 cat1
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Burkholderia sp. Q8GAZ6 cat2
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Burkholderia sp. TH2 Q8GAY6 cat1
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Burkholderia sp. TH2 Q8GAZ6 cat2
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0948
-
 CatA1 Burkholderia sp.
3.92
-
 CatA2 Burkholderia sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-chlorocatechol + O2 CatA1: 4.4% of the activity with catechol Burkholderia sp. 2-chloro-cis,cis-muconate
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 ?
3-chlorocatechol + O2 CatA1: 4.4% of the activity with catechol Burkholderia sp. TH2 2-chloro-cis,cis-muconate
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 ?
4-chlorocatechol + O2 CatA1: 18.1% of the activity with catechol Burkholderia sp. (2E,4Z)-3-chlorohexa-2,4-dienedioate
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 ?
4-chlorocatechol + O2 CatA2: 2.5% of the activity with catechol Burkholderia sp. (2E,4Z)-3-chlorohexa-2,4-dienedioate
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 ?
4-chlorocatechol + O2 CatA1: 18.1% of the activity with catechol Burkholderia sp. TH2 (2E,4Z)-3-chlorohexa-2,4-dienedioate
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 ?
4-chlorocatechol + O2 CatA2: 2.5% of the activity with catechol Burkholderia sp. TH2 (2E,4Z)-3-chlorohexa-2,4-dienedioate
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 ?
4-methylcatechol + O2 CatA1: 39.5% of the activity with catechol Burkholderia sp. 3-methyl-cis,cis-muconate
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 ?
4-methylcatechol + O2 CatA2: 13.1% of the activity with catechol Burkholderia sp. 3-methyl-cis,cis-muconate
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 ?
4-methylcatechol + O2 CatA1: 39.5% of the activity with catechol Burkholderia sp. TH2 3-methyl-cis,cis-muconate
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 ?
4-methylcatechol + O2 CatA2: 13.1% of the activity with catechol Burkholderia sp. TH2 3-methyl-cis,cis-muconate
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 ?
catechol + O2
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 Burkholderia sp. cis,cis-muconate
-
 ?
catechol + O2 both catechol dioxygenases, CatA1 and CatA2 are produced in benzoate-grown cells, CatA1 is undetectable when strain TH2 is grown on 2-chlorobenzoate or cis,cis-muconate. Production of CatA1 during growth on 2-chlorobenzoate or cis,cis-muconate is observed when cat2 genes are disrupted. The inducer of Cat1 is benzoate. cis,cis-Muconate or its metabolite acts as an inducer for CatA2. Genes are not indispensable for growth of strain TH2 on 2-chlorobenzoate, they are advantageous Burkholderia sp. cis,cis-muconate
-
 ?
catechol + O2
-
 Burkholderia sp. TH2 cis,cis-muconate
-
 ?
catechol + O2 both catechol dioxygenases, CatA1 and CatA2 are produced in benzoate-grown cells, CatA1 is undetectable when strain TH2 is grown on 2-chlorobenzoate or cis,cis-muconate. Production of CatA1 during growth on 2-chlorobenzoate or cis,cis-muconate is observed when cat2 genes are disrupted. The inducer of Cat1 is benzoate. cis,cis-Muconate or its metabolite acts as an inducer for CatA2. Genes are not indispensable for growth of strain TH2 on 2-chlorobenzoate, they are advantageous Burkholderia sp. TH2 cis,cis-muconate
-
 ?
additional information CatA2: no activity with 3-chlorocatechol Burkholderia sp. ?
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 ?
additional information CatA2: no activity with 3-chlorocatechol Burkholderia sp. TH2 ?
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 ?