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Literature summary for 1.13.11.31 extracted from

  • Poeckel, D.; Tausch, L.; Kather, N.; Jauch, J.; Werz, O.
    Boswellic acids stimulate arachidonic acid release and 12-lipoxygenase activity in human platelets independent of Ca2+ and differentially interact with platelet-type 12-lipoxygenase (2006), Mol. Pharmacol., 70, 1071-1078.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
beta-boswellic acid 0.03 mM, in the absence of Ca2+ Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
3-O-acetyl-11-keto-boswellic acid 0.03 mM Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ 1 mM Ca2+-dependent activity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood platelet
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonate + O2
-
Homo sapiens (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
-
?

Synonyms

Synonyms Comment Organism
12-lipoxygenase
-
Homo sapiens
p12-LO
-
Homo sapiens
platelet-type 12-lipoxygenase
-
Homo sapiens