Cloned (Comment) | Organism |
---|---|
RAW 267.4 murine macrophages stably transfected to overexpress 15-LO-1 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonate + O2 | - |
Homo sapiens | (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
15(S)-lipoxygenase-1 | - |
Homo sapiens |
15-LO-1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | overexpression of human 15-LO-1 in RAW macrophages promotes reverse cholesterol transport through increased cholesteryl ester hydrolysis and ABCA1-mediated cholesterol efflux | Homo sapiens |