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Literature summary for 1.13.11.33 extracted from

  • Zhao, J.; ODonnell, V.B.; Balzar, S.; St Croix, C.M.; Trudeau, J.B.; Wenzel, S.E.
    15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells (2011), Proc. Natl. Acad. Sci. USA, 108, 14246-14251.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens 15LO1 interacts with PEBP1 (phosphatidylethanolamine-binding protein) ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epithelial cell airway epithelial cell Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information 15LO1 interacts with PEBP1 (phosphatidylethanolamine-binding protein) Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
15-lipoxygenase 1
-
 Homo sapiens
15LO1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens 15LO1 is highly expressed in fresh epithelial cells from severe asthmatic patients up

General Information

General Information Comment Organism
physiological function high levels of 15LO1 interact with PEBP1 to displace Raf-1 and sustain MAPK/ERK activation Homo sapiens