Literature summary for 1.13.11.34 extracted from

Cashman, J.R.; Lambert, C.; Sigal, E.
Inhibition of human leukocyte 5-lipoxygenase by 15-HPETE and related eicosanoids (1988), Biochem. Biophys. Res. Commun., 155, 38-44.

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Inhibitors

Inhibitors	Comment	Organism	Structure
15-hydroperoxy-6,8,11,13-eicosatetraenoic acid	IC50: 0.0048 mM	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leukocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
arachidonate + O2	i.e. 5,8,11,14-eicosatetraenoic acid	Homo sapiens	(6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate	-	?

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0048	-	IC50: 0.0048 mM	Homo sapiens	15-hydroperoxy-6,8,11,13-eicosatetraenoic acid

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Release 2023.1 (January 2023)