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Literature summary for 1.13.11.34 extracted from

  • Pande, A.H.; Moe, D.; Nemec, K.N.; Qin, S.; Tan, S.; Tatulian, S.A.
    Modulation of human 5-lipoxygenase activity by membrane lipids (2004), Biochemistry, 43, 14653-14666.
    View publication on PubMed
Search for more literature for 1.13.11.34

Activating Compound

Activating Compound Comment Organism Structure
phosphatidylcholine enzyme activity is supported by phosphatidylcholine more than by any other lipid tested, except for a cationic lipid, which is more stimulatory than phosphatidylcholine Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane the enzyme is activated by a Ca2+-mediated translocation to membranes. The enzyme binds to membranes at a defined orientation with the symmetry axis of the putative N-terminal beta-barrel tilted about 45° from the membrane normal Homo sapiens 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ the enzyme is activated by a Ca2+-mediated translocation to membranes Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
5-LO
-
 Homo sapiens