Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenylacetic acid | micromolar 5-LOX inhibitory activity | Solanum tuberosum | |
2-[2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl]propanoic acid | micromolar 5-LOX inhibitory activity | Solanum tuberosum | |
2-[3-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl]propanoic acid | micromolar 5-LOX inhibitory activity | Solanum tuberosum | |
2-[4-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl]propanoic acid | micromolar 5-LOX inhibitory activity | Solanum tuberosum | |
3-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenylacetic acid | micromolar 5-LOX inhibitory activity | Solanum tuberosum | |
4-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenylacetic acid | micromolar 5-LOX inhibitory activity | Solanum tuberosum | |
caffeic acid | micromolar 5-LOX inhibitory activity | Solanum tuberosum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Solanum tuberosum | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
5-lipoxygenase | - |
Solanum tuberosum |
5-LOX | - |
Solanum tuberosum |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0002 | - |
pH and temperature not specified in the publication | Solanum tuberosum | 2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenylacetic acid | |
0.00037 | - |
pH and temperature not specified in the publication | Solanum tuberosum | 3-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenylacetic acid | |
0.00037 | - |
pH and temperature not specified in the publication | Solanum tuberosum | 2-[3-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl]propanoic acid | |
0.002 | - |
pH and temperature not specified in the publication | Solanum tuberosum | 2-[2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl]propanoic acid | |
0.003 | - |
pH and temperature not specified in the publication | Solanum tuberosum | 2-[4-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenyl]propanoic acid | |
0.00347 | - |
pH and temperature not specified in the publication | Solanum tuberosum | 4-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)phenylacetic acid | |
0.004 | - |
pH and temperature not specified in the publication | Solanum tuberosum | caffeic acid |