Any feedback?
Literature summary for 1.13.11.52 extracted from
- Tryptophan degraadation in mice initiated by indoleamine 2,3-dioxygenase (1986), J. Biol. Chem., 261, 3648-3653.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| bacterial lipopolysaccharide | - |
Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
male specific-pathogen-free ICR mice | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| homogenization | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Mus musculus | - |
| cecum | - |
Mus musculus | - |
| colon | - |
Mus musculus | - |
| epididymis | - |
Mus musculus | - |
| esophagus | - |
Mus musculus | - |
| heart | - |
Mus musculus | - |
| intestine | - |
Mus musculus | - |
| kidney | - |
Mus musculus | - |
| lung | - |
Mus musculus | - |
| seminal vesicle | - |
Mus musculus | - |
| spleen | - |
Mus musculus | - |
| stomach | - |
Mus musculus | - |
| submandibular gland | - |
Mus musculus | - |
| testis | - |
Mus musculus | - |
| thymus | - |
Mus musculus | - |
| trachea | - |
Mus musculus | - |
| urinary bladder | - |
Mus musculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.07 | - |
esophagus | Mus musculus |
| 0.122 | - |
submandibular gland | Mus musculus |
| 0.13 | - |
testis | Mus musculus |
| 0.155 | - |
kidney | Mus musculus |
| 0.165 | - |
brain | Mus musculus |
| 0.183 | - |
heart | Mus musculus |
| 0.232 | - |
brain, lipopolysaccharide-treated mice | Mus musculus |
| 0.24 | - |
kidney, lipopolysaccharide-treated mice | Mus musculus |
| 0.278 | - |
esophagus, lipopolysaccharide-treated mice | Mus musculus |
| 0.342 | - |
submandibular gland, lipopolysaccharide-treated mice | Mus musculus |
| 0.375 | - |
stomach | Mus musculus |
| 0.425 | - |
thymus | Mus musculus |
| 0.45 | - |
lung | Mus musculus |
| 0.468 | - |
cecum | Mus musculus |
| 0.56 | - |
testis, lipopolysaccharide-treated mice | Mus musculus |
| 0.57 | - |
heart, lipopolysaccharide-treated mice | Mus musculus |
| 0.72 | - |
seminal vesicle | Mus musculus |
| 0.735 | - |
trachea, lipopolysaccharide-treated mice | Mus musculus |
| 0.755 | - |
spleen, lipopolysaccharide-treated mice | Mus musculus |
| 0.8 | - |
thymus, lipopolysaccharide-treated mice | Mus musculus |
| 0.903 | - |
colon | Mus musculus |
| 0.92 | - |
spleen | Mus musculus |
| 0.968 | - |
trachea | Mus musculus |
| 1.39 | - |
urinary bladder, lipopolysaccharide-treated mice | Mus musculus |
| 1.455 | - |
urinary bladder | Mus musculus |
| 1.902 | - |
stomach, lipopolysaccharide-treated mice | Mus musculus |
| 2.017 | - |
intestine | Mus musculus |
| 4.07 | - |
intestine, lipopolysaccharide-treated mice | Mus musculus |
| 5.34 | - |
lung, lipopolysaccharide-treated mice | Mus musculus |
| 8.33 | - |
seminal vesicle, lipopolysaccharide-treated mice | Mus musculus |
| 15.31 | - |
cecum, lipopolysaccharide-treated mice | Mus musculus |
| 26.68 | - |
colon, lipopolysaccharide-treated mice | Mus musculus |
| 32.22 | - |
epididymis | Mus musculus |
| 104.9 | - |
epididymis, lipopolysaccharide-treated mice | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| kynurenine | - |
Mus musculus | ? | - |
? |  |
| L-tryptophan + O2 | - |
Mus musculus | N-formyl-L-kynurenine | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0015 | - |
kynurenine | LPS-treated mice | Mus musculus | |
| 0.002 | - |
kynurenine | - |
Mus musculus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
