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Literature summary for 1.13.11.59 extracted from

  • Estrada, A.F.; Maier, D.; Scherzinger, D.; Avalos, J.; Al-Babili, S.
    Novel apocarotenoid intermediates in Neurospora crassa mutants imply a new biosynthetic reaction sequence leading to neurosporaxanthin formation (2008), Fungal Genet. Biol., 45, 1497-1505.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Neurospora crassa

Protein Variants

Protein Variants Comment Organism
additional information expression in 3,4-didehydrolycopene accumulating Escherichia coli leads to apo-4'-lycopenal Neurospora crassa

Organism

Organism UniProt Comment Textmining
Neurospora crassa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-didehydrolycopene + O2 Cao2 accepts both cyclic and acyclic carotenals Neurospora crassa apo-4'-lycopenal + 3-methylbut-2-enal
-
?

Synonyms

Synonyms Comment Organism
Cao2
-
Neurospora crassa

General Information

General Information Comment Organism
physiological function enzyme is involved in the biosynthetic pathway to neurosporaxanthin. First step is the cleavage of 3,4-didehydrolycopene into apo-4'-lycopenal by Cao2, which is then oxidized by YLO-1 to yield apo-4'-lycopenoic acid, the last intermediate in the pathway. The final step is then catalyzed by the cyclase activity of AL-2 Neurospora crassa