Literature summary for 1.13.11.63 extracted from

Lakshamanan, M.R.; Chansang, H.; Olson, J.A.
Purification and properties of carotene 15,15-dioxygenase of rabbit intestine (1972), J. Lipid Res., 13, 477-482.

Search for more literature for 1.13.11.63

Inhibitors

Inhibitors	Comment	Organism	Structure
1,10-phenanthroline	-	Oryctolagus cuniculus
15,15'-Dehydro-beta-apo-10'-carotenol	inhibits reaction with beta-apo-10'-carotenol	Oryctolagus cuniculus
2,2'-dipyridyl	-	Oryctolagus cuniculus
iodoacetamide	-	Oryctolagus cuniculus
NEM	-	Oryctolagus cuniculus
PCMB	reversed by glutathione	Oryctolagus cuniculus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.067	-	beta-apo-10'-carotenol + O2	-	Oryctolagus cuniculus

Organism

Organism	UniProt	Comment	Textmining
Clarias batrachus	-	-	-
Domania subtryug	-	-	-
Gallus gallus	-	-	-
no activity in Felis catus	-	intestine	-
Oryctolagus cuniculus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Oryctolagus cuniculus

Source Tissue

Source Tissue	Comment	Organism	Textmining
intestine	mucosa	Gallus gallus	-
intestine	mucosa	Oryctolagus cuniculus	-
intestine	mucosa	Clarias batrachus	-
intestine	mucosa	Domania subtryug	-
intestine	pylorus to the lower ileum	Oryctolagus cuniculus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.000035	-	-	Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
beta-apo-10'-carotenol + O2	-	Oryctolagus cuniculus	?	-	r

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.8	-	reaction with beta-apo-10'-carotenol	Oryctolagus cuniculus

pH Range

pH Minimum	pH Maximum	Comment	Organism
7	9	pH 7.0: about 50% of maximal activity, pH 9.0: about 35% of maximal activity, reaction with beta-apo-10'-carotenol	Oryctolagus cuniculus

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Release 2023.1 (January 2023)