Literature summary for 1.13.11.63 extracted from

Ferrucci, L.; Perry, J.R.; Matteini, A.; Perola, M.; Tanaka, T.; Silander, K.; Rice, N.; Melzer, D.; Murray, A.; Cluett, C.; Fried, L.P.; Albanes, D.; Corsi, A.M.; Cherubini, A.; Guralnik, J.; Bandinelli, S.; Singleton, A.; Virtamo, J.; Walston, J.; Semba, R.D.; Frayling, T.M.
Common variation in the beta-carotene 15,15-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study (2009), Am. J. Hum. Genet., 84, 123-133.

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
beta-carotene + O2	Homo sapiens	two molecules retinal are formed	retinal	-	?

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9HAY6	-	-

Source Tissue	Comment	Organism	Textmining
blood	-	Homo sapiens	-
small intestine	-	Homo sapiens	-

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
alpha-carotene + O2	one molecule retinal is formed	Homo sapiens	retinal + ?	-	?
beta-carotene + O2	two molecules retinal are formed	Homo sapiens	retinal	-	?
beta-criptoxanthin + O2	one molecule retinal is formed	Homo sapiens	retinal + ?	-	?
additional information	catalyses the first step in the conversion of dietary provitamin A carotenoids to vitamin A in the small intestine	Homo sapiens	?	-	?

Synonyms	Comment	Organism
Bcmo1	-	Homo sapiens
beta-carotene 15,15'-monooxygenase	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)