Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Mus musculus |
expression in Escherichia coli | Rattus norvegicus |
expression in Escherichia coli | Homo sapiens |
General Stability | Organism |
---|---|
after storage at 4°C for few weeks, a specific truncation due to degradation is observed, extended storage also causes the accumulation of a small proportion of apparantly dimerized MIOX | Mus musculus |
after storage at 4°C for few weeks, a specific truncation due to degradation is observed, extended storage also causes the accumulation of a small proportion of apparantly dimerized MIOX | Rattus norvegicus |
after storage at 4°C for few weeks, a specific truncation due to degradation is observed, extended storage also causes the accumulation of a small proportion of apparantly dimerized MIOX | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3.3 | - |
myo-inositol | MIOX activity present in peak 1 of hydrophobic-interaction chromatography on Resource-PHE column | Mus musculus | |
3.5 | - |
myo-inositol | MIOX activity present in peak 3 of hydrophobic-interaction chromatography on Resource-PHE column | Homo sapiens | |
5.8 | - |
myo-inositol | MIOX activity present in peak 1 of hydrophobic-interaction chromatography on Resource-PHE column | Homo sapiens | |
8.8 | - |
myo-inositol | MIOX activity present in peak 3 of hydrophobic-interaction chromatography on Resource-PHE column | Mus musculus | |
14.6 | - |
myo-inositol | MIOX activity present in peak 2 of hydrophobic-interaction chromatography on Resource-PHE column | Rattus norvegicus | |
24.7 | - |
myo-inositol | MIOX activity present in peak 2 of hydrophobic-interaction chromatography on Resource-PHE column | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33000 | - |
1 * 33000, deduced from nucleotide sequence, SDS-PAGE | Mus musculus |
33000 | - |
1 * 33000, deduced from nucleotide sequence, SDS-PAGE | Rattus norvegicus |
33000 | - |
1 * 33000, deduced from nucleotide sequence, SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
myo-inositol + O2 | Mus musculus | first commited step in myo-inositol catabolism | D-glucuronic acid + H2O | - |
ir | |
myo-inositol + O2 | Rattus norvegicus | first commited step in myo-inositol catabolism | D-glucuronic acid + H2O | - |
ir | |
myo-inositol + O2 | Homo sapiens | first commited step in myo-inositol catabolism | D-glucuronic acid + H2O | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9UGB7 | - |
- |
Mus musculus | Q9QXN5 | - |
- |
Rattus norvegicus | Q9QXN4 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant MIOX | Mus musculus |
recombinant MIOX | Rattus norvegicus |
recombinant MIOX | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Mus musculus | - |
kidney | - |
Rattus norvegicus | - |
kidney | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
myo-inositol + O2 | - |
Mus musculus | D-glucuronic acid + H2O | - |
ir | |
myo-inositol + O2 | - |
Rattus norvegicus | D-glucuronic acid + H2O | - |
ir | |
myo-inositol + O2 | - |
Homo sapiens | D-glucuronic acid + H2O | - |
ir | |
myo-inositol + O2 | first commited step in myo-inositol catabolism | Mus musculus | D-glucuronic acid + H2O | - |
ir | |
myo-inositol + O2 | first commited step in myo-inositol catabolism | Rattus norvegicus | D-glucuronic acid + H2O | - |
ir | |
myo-inositol + O2 | first commited step in myo-inositol catabolism | Homo sapiens | D-glucuronic acid + H2O | - |
ir |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 33000, deduced from nucleotide sequence, SDS-PAGE | Mus musculus |
monomer | 1 * 33000, deduced from nucleotide sequence, SDS-PAGE | Rattus norvegicus |
monomer | 1 * 33000, deduced from nucleotide sequence, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
MIOX | - |
Mus musculus |
MIOX | - |
Rattus norvegicus |
MIOX | - |
Homo sapiens |