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Literature summary for 1.14.11.11 extracted from

  • Yun, D.J.; Hashimoto, T.; Yamada, Y.
    Transgenic tobacco plants with two consecutive oxidation reactions catalyzed by hyoscyamine 6b-hydroxylase (1993), Biosci. Biotechnol. Biochem., 57, 502-503.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-hyoscyamine + 2-oxoglutarate + O2 Hyoscyamus niger the enzyme catalyzes two consecutive oxidation reactions leading from hyoscyamine to scopolamine 6beta-hydroxyhyoscyamine + succinate + CO2
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Organism

Organism UniProt Comment Textmining
Hyoscyamus niger
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6beta-hydroxyhyoscyamine weak epoxidase activity, 2-5% of the hydroxylase activity Hyoscyamus niger scopolamine
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L-hyoscyamine + 2-oxoglutarate + O2
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Hyoscyamus niger 6beta-hydroxyhyoscyamine + succinate + CO2
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?
L-hyoscyamine + 2-oxoglutarate + O2 the enzyme catalyzes two consecutive oxidation reactions leading from hyoscyamine to scopolamine Hyoscyamus niger 6beta-hydroxyhyoscyamine + succinate + CO2
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?