Activating Compound | Comment | Organism | Structure |
---|---|---|---|
bovine serum albumin | activation | Gallus gallus | |
bovine serum albumin | activation | Homo sapiens | |
catalase | activation | Gallus gallus | |
catalase | activation | Homo sapiens | |
dithiothreitol | activation | Gallus gallus | |
dithiothreitol | activation | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyloxycarbonyl-Phe-Opr-Gly-benzyl ester | 50% inactivation in 1 h at 0.0008 mM, the most effective inhibitor within oxaproline peptides | Gallus gallus | |
benzyloxycarbonyl-Phe-Opr-Gly-benzyl ester | 50% inactivation in 1 h at 0.0008 mM, the most effective inhibitor within oxaproline peptides | Homo sapiens | |
additional information | synthetic peptides containing the non-physiologic amino acid 5-oxaproline in the sequence R1-Xaa-oxaproline-Gly-OR2 are specific syncatalytic inactivators, noncompetitive inhibition with respect to peptide substrate and ascorbate, compounds with aromatic substituents R1 and R2 are particularly effective when compared with those with an aliphatic group, inactivation is only observed in the presence of Fe2+ and 2-oxoglutarate | Gallus gallus | |
additional information | synthetic peptides containing the non-physiologic amino acid 5-oxaproline in the sequence R1-Xaa-oxaproline-Gly-OR2 are specific syncatalytic inactivators, noncompetitive inhibition with respect to peptide substrate and ascorbate, compounds with aromatic substituents R1 and R2 are particularly effective when compared with those with an aliphatic group, inactivation is only observed in the presence of Fe2+ and 2-oxoglutarate | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Gallus gallus | |
additional information | - |
additional information | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | - |
Gallus gallus | |
Fe2+ | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
using ammonium sulfate fractionation, affinity chromatography on poly(L-proline) coupled to Sepharose 4B, DEAE-cellulose chromatography, and gel filtration | Gallus gallus |
using ammonium sulfate fractionation, affinity chromatography on poly(L-proline) coupled to Sepharose 4B, DEAE-cellulose chromatography, and gel filtration | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | - |
Gallus gallus | - |
placenta | - |
Homo sapiens | - |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Gallus gallus |
37 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ascorbate | - |
Gallus gallus | |
ascorbate | - |
Homo sapiens |