Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
procollagen L-proline + 2-oxoglutarate + O2 | Homo sapiens | - |
procollagen trans-4-hydroxy-L-proline + succinate + CO2 | - |
? | |
procollagen L-proline + 2-oxoglutarate + O2 | Rattus norvegicus | - |
procollagen trans-4-hydroxy-L-proline + succinate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
chondroblastoma cell | - |
Homo sapiens | - |
chondrocyte | - |
Homo sapiens | - |
chondrosarcoma cell | predominantly type I prolyl-4-hydroxylase | Homo sapiens | - |
osteochondroma cell | - |
Homo sapiens | - |
osteosarcoma cell | ATCC ROS 17/2.8, strong expression of type I alpha subunit | Rattus norvegicus | - |
osteosarcoma cell | predominantly type I prolyl-4-hydroxylase | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
procollagen L-proline + 2-oxoglutarate + O2 | - |
Homo sapiens | procollagen trans-4-hydroxy-L-proline + succinate + CO2 | - |
? | |
procollagen L-proline + 2-oxoglutarate + O2 | - |
Rattus norvegicus | procollagen trans-4-hydroxy-L-proline + succinate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
type I proly 4-hydroxylase | - |
Rattus norvegicus |
type I proyl 4-hydroxylase | - |
Homo sapiens |
type II proyl 4-hydroxylase | - |
Homo sapiens |