Inhibitors | Comment | Organism | Structure |
---|---|---|---|
S-nitroso-N-acetylpenicillamine | hyperoxia attenuates the inhibitory effect of NO on HIF-1alpha prolyl hydroxylation | Homo sapiens | |
S-nitrosoglutathione | hyperoxia attenuates the inhibitory effect of NO on HIF-1alpha prolyl hydroxylation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
biotin-Ahx-DLDLEALAP564YIPADDDFQL + 2-oxoglutarate + O2 | 19mer HIF peptide not containing cysteine is used, in order to rule out an involvement of the cysteine nitrosylation | Homo sapiens | ? | - |
? | |
hypoxia-inducible factor L-proline + 2-oxoglutarate + O2 | - |
Homo sapiens | hypoxia-inducible factor trans-4-hydroxy-L-proline + succinate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HPH-2 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |