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Literature summary for 1.14.11.41 extracted from

  • Ju, J.; Ozanick, S.G.; Shen, B.; Thomas, M.,G.
    Conversion of (2S)-arginine to (2S,3R)-capreomycidine by VioC and VioD from the viomycin biosynthetic pathway of Streptomyces sp. strain ATCC11861 (2004), Chembiochem, 5, 1281-1285.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Escherichia coli with an N-terminal hexahistidine affinity tag Streptomyces sp.

Organism

Organism UniProt Comment Textmining
Streptomyces sp.
-
-
-
Streptomyces sp. ATCC 11861
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Streptomyces sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + 2-oxoglutarate + O2
-
Streptomyces sp. (3S)-3-hydroxy-L-arginine + succinate + CO2
-
?
L-arginine + 2-oxoglutarate + O2
-
Streptomyces sp. ATCC 11861 (3S)-3-hydroxy-L-arginine + succinate + CO2
-
?

Synonyms

Synonyms Comment Organism
VioC
-
Streptomyces sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Streptomyces sp.

General Information

General Information Comment Organism
physiological function the enzyme is involved in the biosynthesis of viomycin (an antibiotic of the tuberactinomycin family) Streptomyces sp.