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Literature summary for 1.14.12.19 extracted from
- Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12 (1998), J. Bacteriol., 180, 2915-2923.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Salmonella typhimurium | Escherichia coli |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 11328 | - |
gene products from hcaA1, hcaA2, hcaC and hcaD, 1 * 51109 + 1 * 20579 + 1 * 11328 + 1 * 43978, subunit masses calculated from deduced amino acid sequences | Escherichia coli |
| 20579 | - |
gene products from hcaA1, hcaA2, hcaC and hcaD, 1 * 51109 + 1 * 20579 + 1 * 11328 + 1 * 43978, subunit masses calculated from deduced amino acid sequences | Escherichia coli |
| 43978 | - |
gene products from hcaA1, hcaA2, hcaC and hcaD, 1 * 51109 + 1 * 20579 + 1 * 11328 + 1 * 43978, subunit masses calculated from deduced amino acid sequences | Escherichia coli |
| 51109 | - |
gene products from hcaA1, hcaA2, hcaC and hcaD, 1 * 51109 + 1 * 20579 + 1 * 11328 + 1 * 43978, subunit masses calculated from deduced amino acid sequences | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-phenylpropionate + NADH + H+ + O2 | Escherichia coli | enables utilization of 3-phenylpropionate as carbon source, important role in wine making, aging and storage | 3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dien-1-yl]propanoic acid + NAD+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-phenylpropionate + NADH + H+ + O2 | - |
Escherichia coli | 3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dien-1-yl]propanoic acid + NAD+ | - |
? | |
| 3-phenylpropionate + NADH + H+ + O2 | enables utilization of 3-phenylpropionate as carbon source, important role in wine making, aging and storage | Escherichia coli | 3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dien-1-yl]propanoic acid + NAD+ | - |
? | |
| cinnamic acid + NADH + H+ + O2 | - |
Escherichia coli | cinnamic acid-2,3-dihydrodiol + NAD+ | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | gene products from hcaA1, hcaA2, hcaC and hcaD, 1 * 51109 + 1 * 20579 + 1 * 11328 + 1 * 43978, subunit masses calculated from deduced amino acid sequences | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 3-phenylpropionate dioxygenase | - |
Escherichia coli |
| Hca dioxygenase | - |
Escherichia coli |
| HcaA1A2CD | - |
Escherichia coli |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Escherichia coli | |
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